Scientists discover brain switches that clear Alzheimer’s plaques

Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s disease. By stimulating these receptors in mice, scientists increased levels of a natural amyloid-breaking enzyme, reduced buildup in the brain, and improved memory-related behavior.

Because these receptors are common drug targets, the findings could open the door to affordable pill-based treatments with fewer side effects. Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s disease.

By stimulating these receptors in mice, scientists increased levels of a natural amyloid-breaking enzyme, reduced buildup in the brain, and improved memory-related behavior. Because these receptors are common drug targets, the findings could open the door to affordable pill-based treatments with fewer side effects.